mulberry bags Different routes of administration o

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Different routes of administration of misoprostol to terminate early pregnancy of

100 Tianjin Nankai Hospital of Tianjin Medical August 2002 Vol 30 No. 8 497 Table 3 Average fetal sac from the time of complete abortion ,[link widoczny dla zalogowanych], vaginal bleeding after abortion ,[link widoczny dla zalogowanych], menstruation recovery time ,[link widoczny dla zalogowanych], via the number of days (± S) P <0.05. P <0. O1 cells to increase secretion of relaxin . Relaxin can not only dissolve uterine endometrial stromal reticular fibers , softening the cervix , promote the discharge of gestational sac and decidua stripping ; simultaneous inhibition of spontaneous uterine contractions and prostaglandin and oxytocin induced uterine contractions , so that decidual stranded Palace Cavity, caused by bleeding after medical abortion a long time . Granule cells also have a variety of other biological activities , travel through the blood vessel wall into the decidua , the impact of the local detachment of decidual , endometrial regeneration , local hemostasis, coagulation and fibrinolysis mechanisms uterine bleeding caused by a long time 】 . 3.2 The information in the bureaucratic part of the remaining villi and decidua , vaginal bleeding after abortion is caused by a long time, the amount of bleeding , and even the main line of clean government operation . Complete abortion rate of misoprostol vaginally in the oral misoprostol , and small doses by the statistically significant difference. Misoprostol vaginal administration of oral bioavailability of 3 times higher than 】 , drug directly on the cervix, absorbs quickly , increasing the local effects of the uterus and cervix , the duration of up to 4h, promote post-abortion bureaucratic contents of the discharge, reduced Post-abortion bleeding time, decreased intraoperative clean government and improve the success rate of complete abortion . 3.3 The data show that vaginal administration of misoprostol can reduce the stimulation of drugs on the gastrointestinal tract and liver metabolism, gastrointestinal tract than oral administration group , but large doses of misoprostol vaginally , the drugs to act on the cervix, the high concentration , strong uterine contractions , contraction arch pain.
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